6 . 824 Final Project
نویسندگان
چکیده
The presented project implements a persistent, fault-tolerant, high-performance key/value store. In order to achieve these goals, the system implements at-most-once semantics, relies upon Paxos for reaching consensus, shards the database across multiple replica groups, persistently stores values to disk, and implements protocols for automatically recovering and updating disk contents upon server reboot. In order to improve performance, the system features two paxos optimizations: a protocol similar to multi-paxos to avoid the dueling leaders problem, and the ability for leaders to send out prepare messages in advance to reduce the required number of RPCs for paxos agreement.
منابع مشابه
Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores
Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum ly...
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DNA array and Western analyses were used to examine the effects of groESL overexpression and host-plasmid interactions on solvent production in Clostridium acetobutylicum ATCC 824. Strain 824(pGROE1) was created to overexpress the groESL operon genes from a clostridial thiolase promoter. The growth of 824(pGROE1) was inhibited up to 85% less by a butanol challenge than that of the control strai...
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We examined the effectiveness of antisense RNA (as RNA) strategies for metabolic engineering of Clostridium acetobutylicum. Strain ATCC 824(pRD4) was developed to produce a 102-nucleotide asRNA with 87% complementarity to the butyrate kinase (BK) gene. Strain ATCC 824(pRD4) exhibited 85 to 90% lower BK and acetate kinase specific activities than the control strain. Strain ATCC 824(pRD4) also ex...
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http://www.sciencemag.org/cgi/content/full/298/5594/824 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/298/5594/824/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...
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The novel nitroimidazopyran agent (S)-PA-824 has potent antibacterial activity against Mycobacterium tuberculosis in vitro and in vivo and is currently in phase II clinical trials for tuberculosis (TB). In contrast to M. tuberculosis, where (R)-PA-824 is inactive, we report here that both enantiomers of PA-824 show potent parasiticidal activity against Leishmania donovani, the causative agent o...
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